Traceability of Polyethylcyanoacrylate nanoparticles through the Stratum Corneum
نویسندگان
چکیده
In this work we follow the polyethylcyanoacrylate nanoparticles through human skin. Photoluminescence (PL) is used to quantify the amount of these nanocarriers into the layers of the skin stratum corneum (SC). To obtain samples of each layer of SC, tape stripping technique was conducted. Reproducible data were obtained, and the nanoparticles’ distribution in each layer of the SC is presented. Possible applications are in the field of pharmaceutical development, especially concerning drug transport through the skin by nanoparticle carriers.
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تاریخ انتشار 2010